Setup, Design & Observations
All you need to go is a spare USB port and away you go. The long, good quality braided cable will give you a fair amount of slack for the more complex desktop arrangements.
In hand, I have to say I am a fan of the anti-fingerprint textured surface that Razer now employ on their contemporary products. It gives good grip, feels nice and doesn't leech sweat or grease from your finger tips. The year old Mamba TE I have used practically every day since release is only just starting to show some signs of smoothing or wear in the finger tip areas (not bad for 1.3 MILLION clicks in DOTA 2 alone!). The shape is very similar to the Naga Chroma, to which lends itself more to a flatter, palm grip rather than a claw or fingertip. Using a palm grip you will find that it is very comfortable while the side buttons are actually easy to find and press. I did get a little confused at times as I kept forgetting that it is not symmetrical and I kept expecting there to be an additional button in the centre/bottom of the ring. This is likely just a case of getting used to it. I did find that at times when I was reverting to my natural claw grip, the raised bony rear-end of the Naga jutting into my palm did start to cause a dull ache. So it isn't something I would recommend to people, if like me, you use a claw grip where you pull the mouse firmly into your hand.
Performance
The DPI can be adjusted in intervals of 50 (using the slider) though you can set it directly to any whole integer by typing any number between 100-16,000. The 5G (PTE) laser sensor is virtually jitter free at all across its entire DPI range. On top of that, it perfectly tracks on practically any surface we have thrown at it. Glossy coloured card, wood, cardboard, white paper, black fabric, coloured fabric, all tracks immensely well. The only time we have found that it starts to falter on is, literally, on glass.
In DOTA2, I found that the Naga Hex V2 was effective and the side buttons were far easier to understand a placement than say, with the standard Naga mouse. As the side buttons are positioned in a way that all the buttons are fairly easy to access (I did struggle a little with 3/6/7 but this seemed to be more a learning curve, rather than a problem with their position). As to whether I genuinely prefer using all my abilities and commands on the mouse is a different matter. Though what I did was, I used my default controls/layout, where I would use the two, most fastest to access buttons on the mouse (4/1 for me) as QW (ability 1/2) then I assigned the various other buttons with some hotkeys, including buy TP scroll, call courier, send courier to secret base, and a Tornado, EMP, Meteor, deafening blast macro for Invoker (just to be a total noob). These options being as accessible as they are on the Naga Hex V2 really made the difference, and compared to the grid layouts on the MMO mice, the button ring, was more intuitive and easier to remember.
As this is a sensor I am very familiar with, it does have a downside despite being very smooth and fast. Meaning it suffers with a small amount of hardware acceleration. For MOBAs, it is not a huge problem but for those that like to dabble with FPSs and swear by a zero acceleration optical sensor (3310, 3366), you may end up sacrificing that little bit of absolute precision. Despite that, I would say that the Razer sensor here is absolutely better than all other laser sensors I have experienced.